Fault Detection and Diagnosis in an Industrial Fed-Batch Cell Culture Process
نویسندگان
چکیده
منابع مشابه
Fault Detection and Diagnosis in Industrial Fed-batch Cell Culture
Multivariate statistical process monitoring techniques are applied to pilot-plant, cell culture data for the purpose of fault detection and diagnosis. Data from 23 batches, 20 normal operating conditions (NOC) and three abnormal, were available. A PCA model was constructed from 19 NOC batches, while the remaining NOC batch was used for model validation. Subsequently, the model was used to succe...
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ژورنال
عنوان ژورنال: Biotechnology Progress
سال: 2007
ISSN: 8756-7938,1520-6033
DOI: 10.1002/bp070063m